鼓励母亲参与婴儿护理的一种方法是通过简单的床边非药物措施，如SSC。大量研究已经证明了SSC在改善婴儿生理稳定性方面的有效性(Feldman-Winter, et al . 2016)。Hiles(2011)通过一个基于证据的项目发现，母亲在给NAS婴儿喂食1小时后进行皮肤对皮肤的护理后，婴儿的睡眠有所改善(引自Maguire, 2014)。霍姆斯(2016)描述了一项皮肤对皮肤/拥抱的倡议，作为一种协调的房间模式和护理的环境控制的一部分，发现接受药物治疗的阿片类药物暴露婴儿的比例减少了41%。Grossman(2015)描述了一个类似的、多层面的支持治疗模型，该模型由287名NAS新生儿组成，可减少住院时间和药物治疗需求。有趣的是，非药物干预被认为等同于药物治疗;当需要更多的干预时，父母的参与就会增加。在一项回顾性队列研究中，Abrahams等人(2007)还发现，避免分离，特别是在生命的关键4-6周，促进了母婴之间的紧密联系，从而减少了戒断症状，减少了对新生儿的治疗干预。鼓励母亲抚摸、抱着、和婴儿说话、看他们的婴儿，不仅对NAS患儿的恢复时间有积极的影响，还能改善婴儿对感官刺激的反应。
One way to encourage a mother’s involvement in her infant’s care can be through simple bedside non-pharmacologic measures such as SSC. Numerous studies have proven the effectiveness of SSC in improving physiologic stability in infants (Feldman-Winter, et al 2016). Through an evidenced-based project, Hiles (2011) found improvements in sleep after mothers implemented skin-to-skin care to NAS infants 1 hour post-feeding (cited in Maguire, 2014). A skin-to-skin/cuddling initiative, part of a coordinated rooming-in model and environmental controls of care described by Holmes (2016), found a 41% reduction in the proportion of opioid-exposed infants treated pharmacologically. A similar, multifaceted model of supportive care initiated with a cohort of 287 NAS neonates described by Grossman (2015) resulted in a decrease in length of stay and need for pharmacological treatment. Interestingly, non-pharmacological interventions were viewed as equivalent to medications; when increased intervention was required, parental involvement was increased. In a retrospective cohort study, Abrahams et al (2007) also found that avoiding separation, particularly in the crucial 4-6 weeks of life, promoted a strengthened mother-infant bond resulting to fewer withdrawal symptoms and required fewer treatment interventions for the newborn. Encouraging mothers to touch, hold, talk to and look at their babies not only has positive effects upon the recovery time of infants with NAS, it also improves the infant’s responses to sensory stimuli .